Structural and Functional Basis of SARS-CoV-2 Entry by...

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Structural and Functional Basis of...

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

Qihui Wang, Yanfang Zhang, Lili Wu, Huan Zhou, Jinghua Yan, Jianxun Qi

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d SARS-CoV-2 interacts with hACE2 via S protein CTD
d A 2.5-A° structure of SARS-CoV-2-CTD in complex with
hACE2 is resolved
d The SARS-CoV-2-CTD displays stronger affinity for hACE2
compared with SARS-RBD
d SARS-CoV-2 -CTD is antigenically different from SARS-RBD

年:

2020

出版社:

Cell Journal

语言:

english

页:

系列:

CC-BY-NC-ND 4.0 International license

文件:

PDF, 4.96 MB

IPFS: